A pathological deficiency in the oxygen-carrying component of the blood, measured in unit volume concentrations of hemoglobin, red blood cell volume, or red blood cell number.
[From Greek an-, without; + haima, blood.]
Below are two studies that show that people who are ANEMIC have a higher prevalence of RLS.
“In this study all new patients referred for anemia to a community-based hematology practice over a 1-year period (March 2011-2012) were included if they had IDA and no RLS treatment. The prevalence of clinically significant RLS (RLS sufferers) was 23.9%, nine times higher than the general population.”
“The prevalence and impact of restless legs syndrome on patients with iron deficiency anemia.” Allen RP, Auerbach S, Bahrain H, Auerbach M, Earley CJ. Am J Hematol. 2013 Apr;88(4):261-4. doi: 10.1002/ajh.23397. Epub 2013 Mar 12.
“Iron deficiency, even at a level too mild to cause anemia, has been linked to restless legs syndrome (RLS) in some people. Some studies have reported RLS in 25 – 30% of people with low iron levels.”
“Restless Leg Syndrome In-Depth Report” The New York Times Online: Health
“Inflammation arising from various etiologies, including infection, autoimmune disorders, chronic diseases, and aging, can promote anemia.”
“Anemia of Inflammation.” Cindy N. Roy. ASH Education Book December 4, 2010 vol. 2010 no. 1 276-280. doi: 10.1182/asheducation-2010.1.276
“The anemia found in patients with chronic infectious, inflammatory, and neoplastic disorders, known as the anemia of chronic disease (ACD), is one of the most common syndromes in medicine, A characteristic finding of the disorders associated with ACD is increased production of the cytokines that mediate the immune or inflammatory response.”
“Advances in the anemia of chronic disease.” Means R.T. Hematology/Oncology Division, Ralph H. Johnson VA Medical Center and the Medical University of South Carolina. International journal of hematology. 1999, vol. 70, no1, pp. 7-12 (61 ref.)
People who are ANEMIC have a higher prevalence of RLS. People who are ANEMIC also have a higher prevalence of INFLAMMATION.