Restless legs syndrome (RLS) is characterized by disturbing leg sensations associated to sleep complaints and excessive daytime somnolence. In the elderly, it affects 10 to 35%. After testing, we conclude that RLS is a prevalent condition in elderly, may lead to sleep complaints and is often underdiagnosed.”
“Restless legs syndrome in institutionalized elderly.” Dantas FG, Medeiros JL, Farias KS, Ribeiro CD. Arq Neuropsiquiatr. 2008 Jun;66(2B):328-30.
“Our findings suggest that restless legs syndrome is relatively common in the elderly and causes significant discomfort and sleep disturbance.”
“Restless legs syndrome in the elderly.” O’Keeffe ST, Noel J, Lavan JN. Postgrad Med J. 1993 Sep;69(815):701-3.
“Chronic low-grade inflammation is a fundamental characteristic of aging.”
“Chronic low-grade inflammation in elderly persons is associated with altered tryptophan and tyrosine metabolism: role in neuropsychiatric symptoms.” Capuron L, Schroecksnadel S, Feart C, Aubert A, Higueret D, Barberger-Gateau P, Laye S, Fuchs D. Biol Psychiatry. 2011 Jul 15;70(2):175-82. doi: 10.1016/j.biopsych.2010.12.006. Epub 2011 Jan 31.
“Chronic systemic inflammation is an underlying cause of many seemingly unrelated, age-related diseases. As humans grow older, systemic inflammation can inflict devastating degenerative effects throughout the body (Ward 1995; McCarty 1999; Brod 2000). This fact is often overlooked by the medical establishment, yet persuasive scientific evidence exists that correcting a chronic inflammatory disorder will enable many of the infirmities of aging to be prevented or reversed. Aging results in an increase of inflammatory cytokines (destructive cell-signaling chemicals) that contribute to the progression of many degenerative diseases (Van der Meide et al. 1996; Licinio et al. 1999).”
“Aging and Inflammation” LifeExtention.com http://www.lef.org/protocols/prtcl-146.shtml